Why zebras don't get ulcers, by Robert M. Sapolsky

Your body is a sophisticated machine. If it were an automobile, it would be a top-of-the-line, luxury-class vehicle with all of the latest options. There’s just one problem: Your body was designed for the savannas of Africa, not the streets and sidewalks of some urban metropolis. This is a major issue due to one of your body’s great fail-safe systems: the stress-response mechanism, also called the “fight-or-flight syndrome.” This mechanism provides your body with its best chance to get away safely from sudden peril, such as when a lion attacks you. It immediately floods your muscles with robust energy. Thus strengthened, you are far more able to evade the hungry predator. Unfortunately, this same stress-response also kicks in during psychological stress. In much of modern city life (even without stalking lions), such stress is often chronic, making your stress-response mechanism work dangerously overtime, and putting your body at risk of numerous stress-related disorders and diseases. Robert M. Sapolsky, a leading neuroendocrinologist, explains it all in this lively and entertaining, yet highly informative book. He writes with delightful, ironic verve and dry, irrepressible wit. He details how chronic stress can undermine your health, and explains what you can do about it, even in the urban jungle.

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If you’re stressed like a normal mammal in an acute physical crisis, the stress response is lifesaving. But if instead you chronically activate the stress response for reasons of psychological stress, your health suffers.
— Robert M. Sapolsky